We live in the Sepik region of Papua New Guinea and due to the remoteness of our setting deal often with malaria. We have been living here for nearly 2 years now and when we arrived we were recommended mefloquine as a preventative. After some severe skin problems that left us fearing liver damage we made the switch to demal 200 on some friends recommendation. We are a family of five with children the ages of 5, 3, and 1 and have been malaria free for 8 months now. We take it every morning and have been amazed at the results. We are recommending this to many friends who work here and have been so fortunate to find something with no side effects now or in the future. Thanks for a great product that works!!