We spent 3 weeks travelling between Johannesburg (SA) and Vilanculos (Mocambique) driving the whole route by car and crossing the border in the Kruger / Limpopo National park. Demal 200 was recommended by a friend who lives in Vilanculos, and who was suffering Malaria for about 10 (!) times before he came in contact with Demal 200. Since then, he has had no problems any more. We used it as described and had no problems with Malaria and also no side effects. In November this year we will travel to Mocambique with Demal 200 again.