I am impressed with Lyme200 & the effects it has had on me & the pathogens. The herxing was pretty legitl & I had to work hard to clean out my system. I have noticed the persistent lingering symptoms slowly disappearing which is GREAT!!! Things I have noticed: My body temp has increased a bit, more energy throughout the day, less malaise & fatigue, better appetite & zest for life coming back to me! Getting my second bottle ordered and looking forward to seeing the continued positive effects with fingers crossed Lyme will be a thing of my past!